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  • jpp
    Junior Member
    • Mar 2009
    • 6

    P2SOLO ONT GPU issue

    Hi everyone,

    We’re experiencing a significant issue with ONT's P2SOLO when running on Windows. Although our computer meets all the hardware and software requirements specified by ONT, it seems that the GPU is not being utilized during basecalling. This results in substantial delays—at times, only about 20% of the data is analyzed in real time.

    We’ve been reaching out to ONT for a while, but unfortunately, they haven’t been able to provide a solution. Has anyone encountered the same problem with the GPU not being used when running MinKNOW? If so, how did you resolve it?

    We’d really appreciate any advice or insights!

    Thanks in advance.
  • frankorgan
    Junior Member
    • Jul 2025
    • 1

    #2
    Originally posted by jpp View Post
    Hi everyone,

    We’re experiencing a significant issue with ONT's P2SOLO when running on Windows. Although our computer meets all the hardware and software requirements specified by ONT, it seems that the GPU is not being utilized during basecalling. This results in substantial delays—at times, only about 20% of the data is analyzed in real time.

    We’ve been reaching out to ONT for a while, but unfortunately, they haven’t been able to provide a block blast solution. Has anyone encountered the same problem with the GPU not being used when running MinKNOW? If so, how did you resolve it?

    We’d really appreciate any advice or insights!

    Thanks in advance.
    It's a persistent problem for some Windows users. Keep pushing ONT support with specific details, and consider the Ubuntu option if it's feasible for your lab. Good luck!

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