Ultimately it is arbitrary. I think the E.coli genome project used a 0 near the replication origin, but that need not be followed.
Another possible landmark would be a well known restriction site, perhaps chosen from some previous work on the organism such as a physical map.
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how to determine the fist position of a genome
most of bacteria genome are circle, but in database most are saved in line. I mean they have first position and last position. I used to believe the ori position, which is replication start point, was defined as first position, now i find i am wrong. how is this defined. any help will appreciated.
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The COVID-19 pandemic highlighted the need for proactive pathogen surveillance systems. As ongoing threats like avian influenza and newly emerging infections continue to pose risks, researchers are working to improve how quickly and accurately pathogens can be identified and tracked. In a recent SEQanswers webinar, two experts discussed how next-generation sequencing (NGS) and machine learning are shaping efforts to monitor viral variation and trace the origins of infectious...03-24-2025, 11:48 AM -
This year’s Advances in Genome Biology and Technology (AGBT) General Meeting commemorated the 25th anniversary of the event at its original venue on Marco Island, Florida. While this year’s event didn’t include high-profile musical performances, the industry announcements and cutting-edge research still drew the attention of leading scientists.
The Headliner
The biggest announcement was Roche stepping back into the sequencing platform market. In the years since...03-03-2025, 01:39 PM
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