As a beginner I might have a stupid question, but I have several VCF files of different individuals that are zipped ( .vcf.gz). I want to merge these files into one VCF file containing all individuals by using vcf-merge.
However, this requires the files to be actually zipped with bgzip and indexed with tabix. Does anyone know if I can go from a .vcf.gz file to a tabix indexed and bgzip file without uncompressing it first (it takes a lot of storage, the files are really big).
Thanks!
However, this requires the files to be actually zipped with bgzip and indexed with tabix. Does anyone know if I can go from a .vcf.gz file to a tabix indexed and bgzip file without uncompressing it first (it takes a lot of storage, the files are really big).
Thanks!