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  • Identifying gene name synonyms

    A quick question.
    Using Entez database or AmiGO, How to you find all synonyms of a particular gene in other genomes without falling back on a sequence homology search.

    For example. Gene psaB can also be annotated as ycf4.

    In fact, I am attempting to identify protein clusters between my newly sequenced genome and the relatives using a script. So, I need to obtain a list of all synonyms.

    Whats the best method, or software.

  • #2
    Originally posted by Jordy224 View Post
    A quick question.
    Using Entez database or AmiGO, How to you find all synonyms of a particular gene in other genomes without falling back on a sequence homology search.

    For example. Gene psaB can also be annotated as ycf4.

    In fact, I am attempting to identify protein clusters between my newly sequenced genome and the relatives using a script. So, I need to obtain a list of all synonyms.

    Whats the best method, or software.
    Have you tried HomoloGene?

    Comment


    • #3
      I currently use the protein cluster application in NCBI
      For example:

      http://www.ncbi.nlm.nih.gov/proteinclusters/624653

      Notice there are multiple names for this single protein, and yet the proteins are homologous. This is just a fact of annotation by the authors.

      It should be possible to compare genomes by protein name as in present or absent without need for time-consuming homology search.

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      • #4
        Hi,

        try using this tool: http://idconverter.bioinfo.cnio.es/IDconverter.php

        it's very good to convert various ID's, give you the result on screen or txt/excel file and you can chose wich database you want to cross-reference,
        Nicolas Tremblay
        Graduate Student

        Cardiovascular Genetics - Andelfinger Lab
        CHU Ste-Justine Research Center

        Comment


        • #5
          thanks for the tool site

          Originally posted by ntremblay View Post
          Hi,

          try using this tool: http://idconverter.bioinfo.cnio.es/IDconverter.php

          it's very good to convert various ID's, give you the result on screen or txt/excel file and you can chose wich database you want to cross-reference,
          Hi,
          Thanks for the tool site. As an ongoing project, I've been trying to work up a non-specialty paper for biologists titled "How to get your text mined" and one of my suggestions is going to be use of the NCBI unique gene id number within the text of any article for publication.

          Comment

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