Can any body tell me what is base calling and calling SNPs?
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I think it depends on the context...
But I'd say that "base calling" is the method by which some software looks at the raw data from your instrument, probably some kind of fluorescence, and decides whether there is an A,C,G or T there.
SNP calling involves comparing this info to a reference sequence, and if there is a discrepancy, deciding if the quality is good enough to justify saying "your sample has a variation"
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...-
Channel: Articles
04-22-2024, 07:01 AM -
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