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I am a newbie to NGS.We are evaluating the possibility of doing CNV analysis by NGS data eigher by Illumina MiSeq or Ion PGM platform on archived melanoma FFPE sample. We donot want high cycle PCR involved in the protocol which may saturate the result. But both Illumina (targetd enrichment) and Ion PGM protocol (template preparation) include high cycle PCR. Does anyone have a good idea? Thanks.
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Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has... -
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
...07-09-2026, 11:10 AM
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