I am a scientist at the Pittsburgh Supercomputing Center, part of the NSF TeraGrid. I am interested in working with bioinformatics researchers to solve the computational challenges presented by next-generation sequencing technologies. I would like to understand how the resources and expertise available at national supercomputing centers can be best applied to this problem.
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NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification,...10-30-2026, 06:46 AM
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