The Dornsife College of Letters, Arts, and Sciences at the University of Southern California is seeking an individual to direct the Genomics Core Facility. The Genomics Core provides state-of-the-art, NextGen sequencing services on Illumina and Ion Torrent platforms, as well as Flow Cytometry and Robotic support (http://upcgenomecore.usc.edu/site/Home.html). The Core provides sample preparation, running/monitoring of the sequencing reactions, and data analysis. The laboratory director will be responsible for managing investigator projects, hiring and supervising research staff, and overseeing all aspects of high throughput DNA sequencing technology management. The laboratory director is expected to proactively monitor technologic development and to work with faculty stakeholders and technical specialists to ensure that USC researchers receive state-of-the-art core services. In addition, the laboratory director will provide guidance to researchers on experimental design and help choosing the appropriate method or technology to address a particular scientific question. Candidates holding a Ph.D. in Molecular Biology or in a related field, as well as computational skills will be preferred. M.Sc. and B. Sc. individuals with extensive experience with experimental design in next generation DNA sequencing systems are also encouraged to apply. Strong organizational, interpersonal and writing skills, the ability to work well in a team environment, and well-developed analytical skills are required. Applicants should submit curriculum vitae, a brief statement of qualifications for the position, and list three references with contact information to Sergey Nuzhdin ([email protected]), John Heidelberg ([email protected]) and Christopher Yokas ([email protected]). The applicants applying before July 15 will be given a full consideration. USC is an equal opportunity employer.
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NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification, detection...-
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Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...-
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