Upcoming Bioinformatics Research Scientist Role at St. Jude Children's Research Hospital - Apply Starting Feb. 2025

[wrosik]

Overview:
The Epigenetics Group, a part of the Center for Applied Bioinformatics (CAB) at St. Jude Children's Research Hospital, is thrilled to announce an upcoming Bioinformatics Research Scientist position. This role will involve developing and applying cutting-edge analytical approaches to uncover the mechanisms driving pediatric cancers and other human diseases. The position will officially open for applications on or around February 10^th 2025, and official application will have to be filled in through the system, but we already invite qualified candidates to forward their CV to wojciech.rosikiewicz[__]stjude.org. This position involves developing and applying innovative analytical approaches to uncover the mechanisms driving pediatric cancers and other human diseases. By contributing to a wide range of projects and assisting researchers across St. Jude, you will make a meaningful impact on science and, ultimately, on the care and survival of pediatric cancer patients.
In addition to performing diverse analytical tasks, we encourage team members to engage in pipeline development, explore novel trends in the field, stay updated on the latest methods, and even create new methodologies—provided these efforts align with our ultimate goal: “Finding cures. Saving children.™”. Our work often leads to high-profile publications, offering significant opportunities for career growth and scientific contributions.

What We Offer:
CAB provides a highly interactive and collaborative environment with opportunities to work alongside experts in transcriptomics, genomics, and genetics, as well as across basic and clinical research departments. Resources include but are not limited to:

• Access to St. Jude's high-performance computing clusters and cloud computing environments.
• Cutting-edge sequencing platforms, such as long-read sequencing technologies, single-cell DNA/RNA sequencing, and spatial transcriptomics.
• Innovative visualization tools and highly automated analytical pipelines powered by GPU technology.
• Mentorship from experienced scientists in data analysis and management, with an expertise in delivering high-quality results for competitive projects.
• Opportunities to participate in and present at scientific conferences, enhancing your expertise and expanding your network.

CAB members have opportunities to contribute to high-impact research, co-author prominent publications, and file patents for novel biomarker discoveries or innovative methods in clinical diagnosis and treatment.

Qualifications:
Ideal candidates will have:

• Experience building, maintaining and optimizing analysis pipelines or installing tools for high-throughput next-generation sequencing data analysis (e.g., ChIP-Seq, ATAC-Seq, RNA-Seq, Hi-C, HiChIP, or Capture-C) in Linux/Unix environments.
• A solid understanding of basic epigenetic gene regulation mechanisms, like histone modifications, chromatin accessibility, DNA methylation or the 3D genome.
• Very good programming skills in Bash scripting language and Python (preferred) or R programming languages.
• Experience with version control systems such as Git.
• Strong communication and project managements skills.
• Experience with deep learningand Nextflow is a plus.

This is an exceptional opportunity to gain experience in diverse areas of bioinformatics, contribute to cutting-edge research, and play a vital role in advancing St. Jude’s mission.

Benefits
St. Jude has frequently received various types of independent “Best Places to Work” awards, like Glassdoor “BEST PLACES TO WORK” awarded this year, and continuously between years 2018 and 2023; the Fortune magazine’s “Best Workplaces in Health Care & Biopharma™ 2020” list, or the Newsweek magazine’s 2023 award for the "America's Greatest Workplaces for Parents and Families". Salary is highly competitive (comparable to industry) and employee benefits are outstanding. This position is located in Memphis, TN, and relocation assistance is available.

Responsibilities

• Specific responsibilities may include NGS data quality control, multi-omics integrative analyses, data visualization, and the development and evaluation of analytic tools. Excellent communication skills are essential. You will collaborate closely with various St. Jude Principal Investigators and their research teams to provide standardized or customized analyses, utilizing St. Jude's high-performance computing clusters and cloud computing environments.

Minimum Education:

• A Bachelor’s degree is required.

Minimum Experience:
Bioinformatics Research Scientist

• Seven (7) years of relevant post-degree work experience is required.
• Five (5) years of relevant post-degree work experience is required with a Master’s degree.
• Two (2) years of relevant post-degree work experience is required with a PhD.

Lead Bioinformatics Analyst

• Six (6) years of relevant experience is required.
• Four (4) years of relevant experience may be acceptable with a Master’s degree.
• No post-degree experience may be acceptable with a PhD in Computer Science or Bioinformatics, coupled with a background in the biological sciences.

Additional Requirements:

• Proficiency in programming (e.g., Python, R, C/C++, Perl, or other programming/scripting languages) in Linux/Unix environments is required.
• Proven ability to work effectively with a wide range of users.
• Demonstrated experience in analyzing and interpreting epigenetics data.
• Proven experience conducting independent data analyses and managing projects is required.
• Experience providing end-user support and training is required.