Unconfigured Ad

Collapse
X
 
  • Time
  • Show
Clear All
new posts
  • xgai
    Junior Member
    • May 2008
    • 9

    #1

    Applications Architect - Children's Hospital Los Angeles

    Job Purpose and Summary:

    Be a critical member of a large precision medicine initiative! Working closely with other bioinformatics and IT staff within the Center for Personalized Medicine, the Applications Architect will create and implement software solutions for managing, processing, transforming, integrating and analyzing a large amount of genomic and clinical data of heterogeneous types. Serve as a technical lead in support of the center’s analytical needs. Design and implement software solutions that adequately address the computational needs of hundreds of terabytes of genomic data with increasing complexity while complying with hospital guidelines and maintaining compliance with regulatory bodies. Implement state-of-the art computational storage and data retrieval methods, and develop innovative analytical methods to enable the implementation of rigorous diagnostic tests. Function both independently and in a team environment to plan, design, develop, modify, and maintain new and existing professional grade databases and database applications. Responsible for all phases of software development life cycle and create deliverables by the end of each stage. Write SOPs and train users. Interact with clients, vendors and hospital IT support group efficiently. Provide IT support for group staff when necessary.

    Preferred Experience:
    • M.S. in Computer Science, Computational Biology, Bioinformatics or related field with 2-5 years of related work experience, or Ph.D. with 1-3 years experience or equivalent

    Knowledge, Skills, Abilities required:
    • Advanced - expert level UNIX/linux background and bash scripting experience
    • Strong programming skills (C++, Java, etc.)
    • Advanced scripting language experience (Perl, Python, Ruby, etc.).
    • Experience in structured and unstructured database development (Oracle/SQL/MySQL/PostgreSQL/MongoDB/NoSQL)
    • Exposure to big data technologies (Pig, Hive, Impala, Hadoop Distributed File System (HDFS), HBase, GPFS)
    • Experience with developing RESTful APIs (XML/JSON/HTML/YAML)
    • Web development and UI experience highly desired (LAMP/HTML/XML/CSS/PHP etc.)
    • Demonstrated ability to implement and understand complex algorithms
    • Demonstrated ability to manage multiple projects and overlapping deadlines
    • Excellent communication skills, both written and verbal

    Additional Skills and Abilities:
    • LIMS experience is a plus
    • EMR/EHR experience/integration is a plus
    • Familiarity with genomic databases/data types is a plus

    For questions, please contact Dr. Xiaowu Gai by email, [email protected].

Latest Articles

Collapse

  • SEQadmin2
    16S/ITS Profiling vs. Shotgun Metagenomics: What Changes in Your Workflow?
    by SEQadmin2




    NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification, detection...
    10-30-2026, 06:46 AM
  • SEQadmin2
    Multiomic Liquid Biopsy: What DNA/RNA Panels Reveal That DNA Alone Can’t
    by SEQadmin2



    Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?

    Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating
    ...
    10-14-2026, 09:55 AM

ad_right_rmr

Collapse

News

Collapse

Topics Statistics Last Post
Started by SEQadmin2, 10-28-2026, 09:57 AM
0 responses
33 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 10-28-2026, 09:51 AM
0 responses
21 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 10-22-2026, 11:13 AM
0 responses
72 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 10-22-2026, 10:48 AM
0 responses
48 views
0 reactions
Last Post SEQadmin2  
Working...