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DNA methylation profiling using HpaII tiny fragment enrichment by ligation-mediated PCR (HELP).
Methods. 2010 Apr 28;
Authors: Suzuki M, Greally JM
The HELP assay is a technique that allows genome-wide analysis of cytosine methylation. Here we describe the assay, its relative strengths and weaknesses, and the transition of the assay from a microarray to massively-parallel sequencing-based foundation.
PMID: 20434563 [PubMed - as supplied by publisher]
More...
DNA methylation profiling using HpaII tiny fragment enrichment by ligation-mediated PCR (HELP).
Methods. 2010 Apr 28;
Authors: Suzuki M, Greally JM
The HELP assay is a technique that allows genome-wide analysis of cytosine methylation. Here we describe the assay, its relative strengths and weaknesses, and the transition of the assay from a microarray to massively-parallel sequencing-based foundation.
PMID: 20434563 [PubMed - as supplied by publisher]
More...