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  • KerryOdair
    Senior Member
    • Sep 2010
    • 123

    #16
    New software Tool From Chris Morley:

    "Dear list,

    I have put together a process for automating the generation of a Geno
    2.0-based Y-SNP phylogeny.

    See my report "An experimental computer-generated Y-chromosomal
    phylogeny, leveraging public Geno 2.0 results and the current ISOGG
    tree" at [ http://ytree.morleydna.com/Experimen...oPhylogeny.pdf ].
    The current ISOGG tree (v. 8.61) was used as the starting point for this
    version of the experimental tree.

    Additionally, [ http://ytree.morleydna.com ] features a Y-SNP subclade
    predictor. Given a set of Y-SNP calls, it will (i) predict the subclade,
    (ii) show the phylogenetic placement (when available) of reported SNPs,
    and (iii) identify unplaced positive SNPs. It can use either the ISOGG
    tree or my experimental tree as the basis for classification. It
    accommodates FTDNA-transferred Geno 2.0 data, and also the Full Genomes
    demo data.

    It's not perfect, but it's a start. It should save some time when
    analysing kits with more than a handful of tested SNPs.

    I invite your feedback.

    Chris Morley"
    FullGenomes Kit 045DV YFull Terminal SNP Y2846 FTDNA Kit 52277 M35>V12>CTS693>CTS3346>Y2877>CTS6667>CTS8411>Y2846 MTdna U4b1a3a

    Comment

    • KerryOdair
      Senior Member
      • Sep 2010
      • 123

      #17
      More information on developments on his new phylogenetic tool

      "Keep in mind that only a finite number of Y-SNPs could be selected for inclusion on the chip, and there are tradeoffs between even coverage and phylogenetic resolution. After a certain point, trying to fit an additional terminal Y-SNP on the chip comes at the expense of leaving out another one -- either a basal Y-SNP, or a phylogenetically redundant Y-SNP from another branch.

      (My next update will feature a separate proof-of-concept phylogeny built using Y-SNP calls from the two Full Genomes demo datasets.) But for those interested in experimenting, future releases of my phylogeny will be accompanied by a CSV summary file with the columns "name, parent, SNPcount, cumuSNPcount, kitCount, cumuKitCount". Expect the next version of my tree later in the week."

      Chris Morley
      FullGenomes Kit 045DV YFull Terminal SNP Y2846 FTDNA Kit 52277 M35>V12>CTS693>CTS3346>Y2877>CTS6667>CTS8411>Y2846 MTdna U4b1a3a

      Comment

      • KerryOdair
        Senior Member
        • Sep 2010
        • 123

        #18
        This is the link to the latest tree from Chris Morely dated 8-Aug-2013

        Y-DNA SNP-based subclade predictor. Determine where your Genographic 2.0 or Full-Y result fits on the most extensive human Y phylogeny. Uncover novel SNPs.


        It appears that he has 75 E1b1b1 tests in this new tree and a total of 1850 Geno 2.0 tests. That is a considerable number which includes tests from other groups than just E-M35.

        He also at the end of the file has two FullGenomes sequenced demo samples using this program.

        This is a link for Geno 2.0 raw data in zip file download format with over 100 samples.

        Last edited by KerryOdair; 08-12-2013, 08:41 AM.
        FullGenomes Kit 045DV YFull Terminal SNP Y2846 FTDNA Kit 52277 M35>V12>CTS693>CTS3346>Y2877>CTS6667>CTS8411>Y2846 MTdna U4b1a3a

        Comment

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