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To assess methylation in the organism, the scientists combined bisulfite treatment of genomic DNA with sequencing on Illumina’s Genome Analyzer and analyzed the data using internally developed computational methods. The approach, called BS-Seq, could be scaled up to study methylation in mammalian genomes, they say.
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To assess methylation in the organism, the scientists combined bisulfite treatment of genomic DNA with sequencing on Illumina’s Genome Analyzer and analyzed the data using internally developed computational methods. The approach, called BS-Seq, could be scaled up to study methylation in mammalian genomes, they say.
More...