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Sequencing fragmented cDNAs on Illumina’s Genome Analyzer and mapping the reads to the yeast genome, the scientists identified untranslated regions, introns, alternative initiation codons, upstream open reading frames, unexpected 3’ ends, and overlapping genes. The results, which appeared online in Science last week, indicate that “the yeast transcriptome is more complex than previously appreciated,” the researchers write in their study, and pave the way for similar analyses of the human genome.
More...
Sequencing fragmented cDNAs on Illumina’s Genome Analyzer and mapping the reads to the yeast genome, the scientists identified untranslated regions, introns, alternative initiation codons, upstream open reading frames, unexpected 3’ ends, and overlapping genes. The results, which appeared online in Science last week, indicate that “the yeast transcriptome is more complex than previously appreciated,” the researchers write in their study, and pave the way for similar analyses of the human genome.
More...