The highest cluster density I've seen (basically top of the PF curve) is around 311,000 PF clusters/tile at 375,000 RAW clusters/tile. On a GAIIx with 120 tiles in a 2x100 run this would give you close to 60G a flowcell. And yes I think this is limitation based on a combination of software and resolution. Push the density much farther and you'll actually start to see PF drop (this has been the case for every version of the pipeline).
Btw, one of the main limiting factors in the hard drive I/O is the awful performance of Dell's PERC5/6 Raid10.
Btw, one of the main limiting factors in the hard drive I/O is the awful performance of Dell's PERC5/6 Raid10.
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