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  • Annotate total variants against reference genome using CLC genomics?

    Hi all, I am a complete novice at CLC genomics, and bioinformatics in general, and, with an absent PI, I am looking to the seqanswers community for help. Is anyone out there proficient enough with CLC genomics workbench to help me? I have done a batch style basic variant detection (0% threshold) of 17 E. coli genomes, all against a single reference genome, so now I have a single track with all the variants detected across all genomes. Next I want to annotate this track against a reference genome to identify more highly variable regions. I have already contacted CLC support, but am hoping to get a faster response on here. I hope this question makes sense.

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