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It weighs a ton and takes up half a room. Why? Any engineers here that knows what's going on inside?
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among other things, laser & optics, filter, cooling for the reagents and the entire interior, a liquid handling robot, an overengineered air table that runs on nitrogen - which was not really needed. -
"..an overengineered air table that runs on nitrogen - which was not really needed" please elaborate
I look at the RSII and a ONT minion and they (skipping some details) pretty much do the same thing (produce long reads). Yet the one requires concrete reinforced floors and the other can be held in your hand. Just find it astounding the difference in scale.Comment
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One of them is an optical platform doing laser based detection of nanometre scale wells, and the other ... isn't. You can't 'skip the details' here, the details are the reasonOriginally posted by BioinformaticsBro View Post"..an overengineered air table that runs on nitrogen - which was not really needed" please elaborate
I look at the RSII and a ONT minion and they (skipping some details) pretty much do the same thing (produce long reads). Yet the one requires concrete reinforced floors and the other can be held in your hand. Just find it astounding the difference in scale.
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PacBio captures videos from single fluorescent molecules that are in a specific location only for milliseconds. Thus, they are trying to avoid any vibrations.Comment
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During the COVID-19 pandemic, scientists observed that while some individuals experienced severe illness when infected with SARS-CoV-2, others were barely affected. These disparities left researchers and clinicians wondering what causes the wide variations in response to viral infections and what role genetics plays.
Jean-Laurent Casanova, M.D., Ph.D., Professor at Rockefeller University, is a leading expert in this crossover between genetics and infectious...09-09-2024, 10:59 AM -
The first FDA-approved CRISPR-based therapy marked the transition of therapeutic gene editing from a dream to reality1. CRISPR technologies have streamlined gene editing, and CRISPR screens have become an important approach for identifying genes involved in disease processes2. This technique introduces targeted mutations across numerous genes, enabling large-scale identification of gene functions, interactions, and pathways3. Identifying the full range...08-27-2024, 04:44 AM
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