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It weighs a ton and takes up half a room. Why? Any engineers here that knows what's going on inside?
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among other things, laser & optics, filter, cooling for the reagents and the entire interior, a liquid handling robot, an overengineered air table that runs on nitrogen - which was not really needed. -
"..an overengineered air table that runs on nitrogen - which was not really needed" please elaborate
I look at the RSII and a ONT minion and they (skipping some details) pretty much do the same thing (produce long reads). Yet the one requires concrete reinforced floors and the other can be held in your hand. Just find it astounding the difference in scale.Comment
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One of them is an optical platform doing laser based detection of nanometre scale wells, and the other ... isn't. You can't 'skip the details' here, the details are the reasonOriginally posted by BioinformaticsBro View Post"..an overengineered air table that runs on nitrogen - which was not really needed" please elaborate
I look at the RSII and a ONT minion and they (skipping some details) pretty much do the same thing (produce long reads). Yet the one requires concrete reinforced floors and the other can be held in your hand. Just find it astounding the difference in scale.
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PacBio captures videos from single fluorescent molecules that are in a specific location only for milliseconds. Thus, they are trying to avoid any vibrations.Comment
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The sequencing world is rapidly changing due to declining costs, enhanced accuracies, and the advent of newer, cutting-edge instruments. Equally important to these developments are improvements in sequencing analysis, a process that converts vast amounts of raw data into a comprehensible and meaningful form. This complex task requires expertise and the right analysis tools. In this article, we highlight the progress and innovation in sequencing analysis by reviewing several of the...Yesterday, 07:48 AM -
The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...04-22-2024, 07:01 AM
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