With the HiSeq platforms (2500 and X), Illumina is dominating genome sequencing (WGS and exome). But for RNA-Seq, does the Proton have a chance? We lay out the case in our latest blog.
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A single-molecule sequencer with an oligo-dT flowcell? -
Well, the Heliscope never sold well, but Helicos didn't really focus on counting applications in the beginning. Perhaps if they had that platform would have found a niche that allowed it to survive. (But you can still use it as a service via SeqLL.com)Originally posted by Chipper View PostComment
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NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification, detection...Today, 06:46 AM -
Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM
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