Tweet
Bioo Scientific recently launched the NEXTflex-HT™ Barcodes, single-index barcodes added during the ligation step of library prep, which offer deep multiplexing for both paired-end and single-read Illumina sequencing. Each barcode contains a unique 12 nt index sequence with a Hamming Distance of five or greater, permitting dual error correction to enable proper differentiation between samples. Additionally, each pair of consecutive barcodes is suitable for low level multiplexing. Currently 384 barcodes are available; however, > 2,000 are being developed.
-
The sequencing world is rapidly changing due to declining costs, enhanced accuracies, and the advent of newer, cutting-edge instruments. Equally important to these developments are improvements in sequencing analysis, a process that converts vast amounts of raw data into a comprehensible and meaningful form. This complex task requires expertise and the right analysis tools. In this article, we highlight the progress and innovation in sequencing analysis by reviewing several of the...05-06-2024, 07:48 AM -
The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...04-22-2024, 07:01 AM