The ability to multiplex a large number of samples in a single run is one of the biggest benefits of using an amplicon-based approach for epidemiological sequencing studies of the SARS-CoV-2 virus as it significantly decreases the turnaround time and cost of analysis. With the ability to multiplex up to 1,536 amplicon libraries in a single run, the NEXTFLEX® DNA-seq kits along with the NEXTFLEX® UDI barcodes deliver a simple, cost-effective solution for adding adapters compatible with Illumina® sequencing to SARS-CoV-2 amplicon pools.
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NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification, detection...Yesterday, 06:46 AM -
Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM