Next-generation sequencing (NGS) is changing how clinical and public health laboratories detect pathogens, track antimicrobial resistance, and respond to outbreaks. However, transforming raw sequencing reads into actionable results is a challenge. Scientists in clinical and public health laboratories need a clear analysis process, an understanding of the quality metrics behind each call, and defined criteria for deciding when a detection counts as positive. Without these, sequencing data can be hard to interpret and turn into a validated clinical workflow.
In this webinar brought to you by BugSeq, Jose Alexander from AdventHealth will explain the basics of NGS analysis and show how to build a sequencing workflow in a clinical lab, including how to set thresholds for reporting positive detections. Jennifer Laplante from the New York State Department of Health will share how her team approaches viral sequencing in a public health setting. To close, Sherif Nour will demo BugSeq's fully automated, cloud-based bioinformatics platform, which analyzes DNA and RNA sequencing data within hours, and show where it fits in an efficient lab workflow.
Topics to be covered:
• The basic principles and key metrics behind NGS data analysis evolutionary insights to clinical applications
• How to set up a lab process that takes NGS data from sequencing through analysis
• How to set threshold criteria for calling positive detections with confidence
• How viral sequencing supports public health surveillance
• How automated, cloud-based bioinformatics can make clinical and public health sequencing workflows faster and simpler
Who should attend:
• Clinical microbiologists and medical microbiologists
• Clinical and public health laboratory directors and managers
• Public health laboratory scientists and epidemiologists working on pathogen surveillance
• Medical technologists and clinical laboratory scientists who are moving into sequencing
• Bioinformaticians who support clinical or public health sequencing workflows
• Infection prevention and antimicrobial stewardship professionals who use sequencing data
• Labs that are evaluating or starting to adopt NGS for pathogen detection
