Hi,
I used a mass spectrometry approach (de novo sequencing) and found single amino acid variations between 2 individuals at the protein level.
I want to test whether this variations are due to SNPs in the DNA or not.
I also need to be able to discriminate heterozygous vs. homozygous variations.
I have 2 samples and 20 "SNPs" to test.
Which method do you recommend?
I am no experience in genomics!
Thanks a lot!
I used a mass spectrometry approach (de novo sequencing) and found single amino acid variations between 2 individuals at the protein level.
I want to test whether this variations are due to SNPs in the DNA or not.
I also need to be able to discriminate heterozygous vs. homozygous variations.
I have 2 samples and 20 "SNPs" to test.
Which method do you recommend?
I am no experience in genomics!
Thanks a lot!
Comment