I've prepared some MeDIP-seq libraries and they appear pretty good and ready to be run on the HiSeq. My question is, do I need to run input control libraries like we do with ChIP-seq or is the fragmentation of the genome and subsequent amplification so even that it is not necessary?
I have samples from several cell lines and was thinking of just running one input control?
I have samples from several cell lines and was thinking of just running one input control?
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