For some reason this information is not readily available. Just want to know who to give the nobel prize to.
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As usual, there is not a simple answer.
Frequently Rollin Hotchkiss is credited, because he was the first to describe "Epi-cytosine" as a distinct, but chemically very similar base to cytosine. (see Fig. 2)
However he established no link to epigenetics and also did not investigate the exact chemical structure of "Epi-Cytosine". The identification as 5mC was achieved by Waldo Cohn in 1951 .
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Researchers using sequencing and genomics tools often have to make trade-offs. They can choose between speed or scale, short reads or long-range information, or targeted panels or a view of the whole transcriptome. New technologies that have been released this year are built to address those tough choices.
We asked six companies the same four questions to learn about their latest products. The new technologies bring a lot to the table, including rethinking sequencing...
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