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I am designing an experiment for detecting miRNA diferential expression in plasma in a follow up experiment. We are going to have a initial cohort with a disease and try to associate some complication or response to miRNA levels. Then we are going to replicate it in a second cohort.
Do someone knows a paper or tutorial or where I should start reading about the porwer calculations for miRNA experiments. Where they differ from the normal power calculation in clasical association studies (like clinical, genotypic, gene expression...)
Do someone knows a paper or tutorial or where I should start reading about the porwer calculations for miRNA experiments. Where they differ from the normal power calculation in clasical association studies (like clinical, genotypic, gene expression...)
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