individual variation in exon usage

ej_duncan

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Join Date: Sep 2013

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individual variation in exon usage

01-22-2014, 10:54 PM

Hi Everyone,

Anyone know of a way of comparing differences in exon usage between individual samples?

I a single tissue type from four individuals and am looking to correlate differences in exon usage with differences in DNA methylation.

I have (for my other projects) been using DEXseq, but this project is designed differently i.e. there are no 'replicates' and no 'treatment'. I want to identify differences in splicing (even if those differences are only in one individual).

Any help/hints/tips would be fantastic (I am a biologist dabbling in some bioinformatics).

-Liz
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