Hi Everyone,
Anyone know of a way of comparing differences in exon usage between individual samples?
I a single tissue type from four individuals and am looking to correlate differences in exon usage with differences in DNA methylation.
I have (for my other projects) been using DEXseq, but this project is designed differently i.e. there are no 'replicates' and no 'treatment'. I want to identify differences in splicing (even if those differences are only in one individual).
Any help/hints/tips would be fantastic (I am a biologist dabbling in some bioinformatics).
-Liz
Anyone know of a way of comparing differences in exon usage between individual samples?
I a single tissue type from four individuals and am looking to correlate differences in exon usage with differences in DNA methylation.
I have (for my other projects) been using DEXseq, but this project is designed differently i.e. there are no 'replicates' and no 'treatment'. I want to identify differences in splicing (even if those differences are only in one individual).
Any help/hints/tips would be fantastic (I am a biologist dabbling in some bioinformatics).
-Liz
