Originally posted by Brian Bushnell
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For example with E. coli, although this is ONE species, but there are various version of it, i.e. sequence type (ST), for example the human adapted E. coli which causes problematic infections around the world is ST131. Between the different sequence types, there might be mutations/genes specific to each of them.
I'm totally new to sequencing. When they are in several contigs, does it mean that there are gaps between the sequences, hence the authors deposited the sequences in contigs rather than a circular 4Mb chromosome?
Many thanks for the advice.
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