Question about transcriptome

[baby1885]

Hello,everyone
When i see some articles about transcriptome,I find something puzzled me is transcript type is processed transcript,unfortunately i really can't understand the "processed transcript" ,anyone who know about it can resolve it for me
Thank you very much!!!

[malachig]

When asking this kind of question, it would be helpful if you provided some specific examples. Post some actual quotes showing usage of that phrase and the citation of the paper you obtained the quote from.

One common meaning of the term "processed transcript" is that the transcript is a mature mRNA molecule as opposed to an unprocessed pre-mRNA molecule. In this context a pre-mRNA is transcribed by an RNA polymerase (i.e. RNA Pol II) and is then "processed" by the splicing machinery to remove introns and connect adjacent exons. Processing could also include the addition of a 5' cap and 3' polyadenylation.

From wikipedia (emphasis is mine):
"A primary transcript is an RNA molecule that has not yet undergone any modification after its synthesis. For example, a precursor messenger RNA (pre-mRNA) is a primary transcript that becomes a messenger RNA (mRNA) after processing, and a primary microRNA transcript (pri-miRNA) becomes a microRNA (miRNA) after processing."
http://en.wikipedia.org/wiki/Primary_transcript

As you can see, the term can refer to miRNA processing as well as mRNA processing. It could also mean something else entirely, but without more context, its difficult to say.

[baby1885]

Thank you malachiq, I have got it!!