We are starting a sequencing core and considering whether to buy a Covaris machine. Do people think fragmentation of gDNA or full-length message cDNA (a la SMARTer ultra low for RNASeq) is going to be best done on a Covaris for the foreseeable future. Or is chemical/enzymatic fragmentation going to become a viable option?
Your carefully considered responses, gut instincts, etc. would be much appreciated.
Eli
Your carefully considered responses, gut instincts, etc. would be much appreciated.
Eli
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