Tweet
Wonder if we can learn something about reference mapping here. We have scRNA-seq data form 10x platform. We want to map barcodes to mouse immune cells. When we will use two references, we got very different results regarding fractions of immune cells. Using one reference, we see more macrophages than dendritic cells; using another reference, we see more dendritic cells than dendritic cells. I am sure someone here may have similar experience? What are your opinions or solutions? Thanks.
-
Spatial biology is an exciting field that encompasses a wide range of techniques and technologies aimed at mapping the organization and interactions of various biomolecules in their native environments. As this area of research progresses, new tools and methodologies are being introduced, accompanied by efforts to establish benchmarking standards and drive technological innovation.
3D Genomics
While spatial biology often involves studying proteins and RNAs in their...01-01-2025, 07:30 PM