what statistics and tool to use?

[chenyao]

You can try sam method, or moderated t-test

[vebaev]

Dear all,
Since I'm not so experienced in statistics most of the time I used deseq.
I have 2 samples with 2 repetitions, and I want to see which are most changed and their p-values.
The problem is in that particular case I do not have simple read counts, but already normalized and calculated by my own way values for a spesific task e.g.
c-control
s-treated

name c1 s1 c2 s2
gene1 0.03 0.1 0.01 0.6

what statistics and what tool I can use and it is most relevant in that case?

Thanks!!!!