Originally posted by KevinLam
View Post
.
-
Nice!
are you intending to write wrappers for galaxy with bfast as well?Leave a comment:
-
BFAST Web Server for the alignment of ABI SOLiD Data
The BFAST Web Server is a user-friendly way to quickly align short reads to reference sequences in both nucleotide space as well as ABI SOLiD color space. Utilities include BFAST alignment, conversion between nucleotide and color space, calculating the a priori power of the alignments, as well as a utility to perform smith-waterman local alignment.
These are demonstration servers only, see please don't hit them with millions (billions) of reads just yet. If anyone desires to set up their own local versions, please contact me and I would be happy to help.
-
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...07-31-2026, 11:01 AM
Leave a comment: