Hello all,
I have a VCF file containing changes in a population of Rattus norvegicus. I would like to rank these changes by the conservation scores of the effected sites. I know that there are various conservation tracks available, they often seem to be mapped to the human genome.
Does anyone know a nice way to retrieve conservation scores for thousands of sites in a non-human genome? I see that some browsers let you view a track but it's not clear to me how to submit sites and get a list of conservation scores. It looks like the most powerful dataset for identifying conserved sites is the 29-mammalian genomes set from the Broad, but I'd be happy to start with other datasets if its simpler to get this information.
Any help or suggestions are greatly appreciated. Thank you in advance!
Cheers,
Rubal
I have a VCF file containing changes in a population of Rattus norvegicus. I would like to rank these changes by the conservation scores of the effected sites. I know that there are various conservation tracks available, they often seem to be mapped to the human genome.
Does anyone know a nice way to retrieve conservation scores for thousands of sites in a non-human genome? I see that some browsers let you view a track but it's not clear to me how to submit sites and get a list of conservation scores. It looks like the most powerful dataset for identifying conserved sites is the 29-mammalian genomes set from the Broad, but I'd be happy to start with other datasets if its simpler to get this information.
Any help or suggestions are greatly appreciated. Thank you in advance!
Cheers,
Rubal
