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Hi,All.
I want to know the difference between human sequence and virus sequence.Is there anyone can help me？
Thanks a lot!
I want to know the difference between human sequence and virus sequence.Is there anyone can help me？
Thanks a lot!
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The human sequence is much longer. -
sorry... I only have short length sequences come from Illumina Hiseq.Originally posted by adaptivegenome View PostComment
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Which virus?
To expand on adaptivegenome's comment, viral genomes tend to be thousands of bases whereas the human genome is billions of bases. However "human" denotes a single species, whereas "virus" could mean any of millions of different organisms. Past that it is difficult to give an answer to such a general question.
If you have some human DNA or RNA that includes viral genomes or transcripts, you could try mapping the Illumina data to the human genome then assembling the non-mapping reads. You could then check the source of the resulting contigs by blasting them against genbank, or some curated database. If you have viral sequence in there it will probably hit other viruses.
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PhillipComment
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I’m not a sequencing expert. I’m a purification scientist who uses NGS to evaluate workflows my group develops. With this perspective, we think about the sample first and the NGS workflow second. The sequencer is an exceptionally honest reporter, but it can only report on what you give it, so whether you get clean, interpretable data from an NGS workflow is largely determined before you begin.
Here are nine questions we think about, in roughly the order they matter, before...06-18-2026, 07:11 AM -
Data variability is still an issue in sequencing technologies despite the advances in reproducibility and accuracy of these platforms. But the problem does not originate in the sequencing itself, but in the previous steps, before the sample reaches the sequencer.
The first step is collection, followed by preservation and sample preparation for analysis. Most scientists overlook those steps, but not being careful might just be skewing the experiment’s results.
...06-02-2026, 10:05 AM
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