Can anyone recommend some reliable software for CNV detection in cancer cells for Illumina WGS data?
-
-
Hi
I am the developer of CNAnorm which is designed for normalisation, segmentation, GC correction and plotting of copy number data from very low coverage (~ 0.05X) whole genome sequencing. It also works with higher coverage (obviously takes more time and you will need a few tweeks) and some report using it sucesfully on exome capture data.
Please read this post where other users posted their questions and I provided some suggestions.
good luck -
Hi, stefanoberri, I am not able to access the paper for CNAnorm, could you mind to send me the paper in mailbox: [email protected]? I appreciate it !Comment
-
Hi, sorry for the late reply.
Here you can find the preprint of the article and the supplemental materialLast edited by stefanoberri; 08-15-2012, 08:47 AM.Comment
-
-
NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification, detection...Today, 06:46 AM -
Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM
Comment