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  • jsun529
    Member
    • Apr 2009
    • 52

    #1

    Nextgen

    What is the mutation detection rate for 454, solexa, and SOLiD if any one have any idea, is there any pub referenced on that ? Thanks
  • westerman
    Rick Westerman
    • Jun 2008
    • 1104

    #2
    There was a paper involving P. stiptis which indicated that all three platforms were able to pick up known SNPs with only a very small false discovery rate and a zero false negative rate. Basically on this small organism and at a high depth of coverage all three platforms work equally well. At least that is what I remember. I don't have the citation off hand so that the above with a grain of salt.

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