What is the mutation detection rate for 454, solexa, and SOLiD if any one have any idea, is there any pub referenced on that ? Thanks
-
-
There was a paper involving P. stiptis which indicated that all three platforms were able to pick up known SNPs with only a very small false discovery rate and a zero false negative rate. Basically on this small organism and at a high depth of coverage all three platforms work equally well. At least that is what I remember. I don't have the citation off hand so that the above with a grain of salt.
-
The immune system’s power comes from its genetic diversity, allowing myriad threats to be neutralized through first recognizing foreign antigens. That diversity is also what makes the immune system so difficult to study. Recent advances in sequencing technology and computational biology, however, are giving researchers new tools to understand immune responses and immune-related diseases in greater detail.
This convergence of genetics, immunology, and computation...Yesterday, 05:41 AM
Comment