I'm trying to find SNPs in a particular CHO cell line, and I'm having trouble finding a SNP database. I've dug through the NCBI ftp looking for a dbsnp file for CHO-K1 cells, and didn't find anything - this seems a little odd, since they have files for things as obscure as pufferfish and elk. Am I right that one doesn't exist? If so, is there a good workaround for masking known polymorphic regions, or am I doomed to paying for massive coverage on the parent cell line? Thanks!
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NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification,...10-30-2026, 06:46 AM -
Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM
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