I'm trying to find SNPs in a particular CHO cell line, and I'm having trouble finding a SNP database. I've dug through the NCBI ftp looking for a dbsnp file for CHO-K1 cells, and didn't find anything - this seems a little odd, since they have files for things as obscure as pufferfish and elk. Am I right that one doesn't exist? If so, is there a good workaround for masking known polymorphic regions, or am I doomed to paying for massive coverage on the parent cell line? Thanks!
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Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM
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