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  • Malobi
    Junior Member
    • Oct 2012
    • 1

    #1

    CoNIFER:CNV detection tool

    I am trying to run conifer and not sure about the SVD normalization like how its is done. How the sample amount effects the analysis quality. what does removal of svd components mean. while calling CNV how on what basis do we set the threshold value? How can we measure the sensitivity and the specificity of the result.
  • omerfaruk
    Member
    • Apr 2013
    • 19

    #2
    You could decide svd value after the first run, looking at the scree plot.

    The higher the control size the merrier

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