Unconfigured Ad

Collapse
X
 
  • Filter
  • Time
  • Show
Clear All
new posts
  • xied75
    Senior Member
    • Feb 2012
    • 129

    Bioinformatics on Windows and Windows Cloud

    For those 92.2% desktop users out there:


    BOW http://bow.codeplex.com/ is my little effort to help you to use your everyday computer on Bioinfo/sequencing.

    Current list of programs: (natively run on Windows x64)
    1, BWA
    2, BWA with multithreaded SAMPE
    3, SAMTOOLS
    4, tabix

    In the making:
    5, SamCompare (a WPF GUI program enable you to compare two SAM/BAM files single/paired end, line by line, tag by tag, to 'debug' your alignment running (i.e. to understand which parameter does what; or to tell if a fancy re-aligner really is that good, just give an example of possible usage.))

    6, SequencingStudio (a WPF GUI program enable you to open all kinds of text/binary files, view with visualization, convert, align, call variant, offload work to the cloud, etc.)

    Beta testing:
    Windows Azure (The Microsoft Cloud) pipleline, I recently did a demo at the Microsoft eScience 2012 workshop of the running system. http://research.microsoft.com/en-US/...12/agenda.aspx, (DemoFest, 12,000 Human Genomes from Raw Sequence to Result, on Windows and Windows Azure ).

    The system is built like a Sun Grid Engine or HPC Cluster in that sense is not limited to process seqence files only. You as a user only need to upload your files to a container, and grab a Recipe (job flow), final results can be in files or databases. The beauty of Cloud is the Utility Model, i.e. you purchase your computing hours like water and electricity, no upfront investment of a local cluster, zero maintenance, zero IT budget/salary. Just a credit card (Purchase Order is accepted too), you can have your own 1000 core cluster up and running in no time, and delete it when your job done.

    It might somehow sounds like Galaxy or BaseSpace, in that 1, I don't know much deep about those systems, 2, my team size is one.

    If you are interested to try out, please contact me. Or you have any suggestions, comments, bricks, programs you want on Windows, etc., just let me know.

    Best,

    dong

    p.s. If you like this thread, maybe kindly ask moderators to pin this on top.
  • a_mt
    Member
    • Jul 2012
    • 34

    #2
    I am so happy today ! My laptop has 4 gb ram and I trying to analyse a small set of data from yeast genome. But god knows for what reason ubuntu (even linux mint !) heats up rapidly and turns off by itself. I was kinda forced to work on windows and I have been trying to install samtools on windows from past 2 days, but both cygwin and mingW kept on giving me error on libraries and headers.

    But today I saw this post and I downloaded samtools and BAM ! works like charm !!

    great job and I hope many users will benefit from this!!

    Thank you.

    Comment

    Latest Articles

    Collapse

    • SEQadmin2
      Cancer Drug Resistance: The Lingering Barrier to Rising Survival
      by SEQadmin2



      Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.

      There is no single reason why many patients don’t respond to treatment as expected. Cancer is...
      Yesterday, 05:17 AM
    • GATTACAT
      Reply to Nine Things a Sample Prep Scientist Thinks About Before Sequencing
      by GATTACAT
      Love this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
      07-01-2026, 11:43 AM
    • SEQadmin2
      Nine Things a Sample Prep Scientist Thinks About Before Sequencing
      by SEQadmin2


      I’m not a sequencing expert. I’m a purification scientist who uses NGS to evaluate workflows my group develops. With this perspective, we think about the sample first and the NGS workflow second. The sequencer is an exceptionally honest reporter, but it can only report on what you give it, so whether you get clean, interpretable data from an NGS workflow is largely determined before you begin.

      Here are nine questions we think about, in roughly the order they matter, before...
      06-18-2026, 07:11 AM

    ad_right_rmr

    Collapse

    News

    Collapse

    Topics Statistics Last Post
    Started by SEQadmin2, Yesterday, 10:08 AM
    0 responses
    6 views
    0 reactions
    Last Post SEQadmin2  
    Started by SEQadmin2, 07-07-2026, 11:05 AM
    0 responses
    8 views
    0 reactions
    Last Post SEQadmin2  
    Started by SEQadmin2, 07-02-2026, 11:08 AM
    0 responses
    31 views
    0 reactions
    Last Post SEQadmin2  
    Started by SEQadmin2, 06-30-2026, 05:37 AM
    0 responses
    29 views
    0 reactions
    Last Post SEQadmin2  
    Working...