Getting familiar with Sequencing

[snz]

Hi all,

I wanted to get an idea about the field of next generation sequencing. More specifically I wanted to know:

1. What are the major computational problems related to next-gen sequencing?
2. Who are some of the notable computational biologists doing research on those problems?
3. What is the goal of sequencing industries? Do they care about compact storage of reads only?
4. What is the goal of biologists that deal with sequencing data?

[colindaven]

Homework ?

[snz]

No, it's not.

[swbarnes2]

You are unlikely to get anyone to answer a question like that.

For starters, look at what you wrote, and calculate how long it looks like you spent on your problem trying to solve it yourself. I'd say, the post demonstrates about 30 seconds worth of effort. If you are asking people to spend 10x as long answering your question as you have spent trying to answer it, well, no one is going to do that.

[Joann]

Visiting Washington DC this summer?

There is a new free exhibit at the Smithsonian Museum of Natural History in Washington DC. You may also navigate the website of the exhibit and its links to find answers to your questions. Follow the links from

http://www.genome.gov/Smithsonian/

Additional information --About this exhibition's funding

Funds for the Smithsonian-NHGRI exhibition and related initiatives were raised privately by both the Smithsonian National Museum of Natural History and the Foundation for the National Institutes of Health.

Life Technologies Foundation, the philanthropic arm of Life Technologies Corp. of Carlsbad, Calif., has pledged $3 million to fund the production of the exhibition itself. Additionally, more than $500,000 has been raised through the Foundation for The National Institutes of Health, Bethesda, Md., and from the Brin Wojcicki Foundation of Palo Alto, Calif.; the Celgene Corporation of Summit, N.J.; Pacific Biosciences of Menlo Park, Calif., Pac Bio president and chief executive officer Mike Hunkapiller, Ph.D., and his wife Beth; the New England Biolabs of Ipswich, Mass.; and from Genentech, Inc. of South San Francisco, Calif.