Driver mutations from mouse tumor WGS data?

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JPreston

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Join Date: Jun 2013

Posts: 17
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#1

Driver mutations from mouse tumor WGS data?

06-26-2013, 02:11 PM

Hello!

I am trying to identify driver mutations from mouse tumor WGS data. I have a list of 1200 SNPs and small indels from an alignment to the mouse mm10 genome and I want to know the names of the genes to see if any SNPs are in known cancer genes. For human data I use mutationassesor.org, but I don't know of a similar tool for mouse data.
Any suggestions would be greatly appreciated!!
Thanks!
Tags: cancer genome, gene finding, mouse, snps
dpryan

Devon Ryan

Join Date: Jul 2011

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#2

06-26-2013, 02:25 PM

Have you tried SnpEff?
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JPreston

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Posts: 17
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#3

06-26-2013, 02:42 PM

That looks great, Thanks!!!
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