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  • ComputGuy
    Junior Member
    • Sep 2013
    • 1
    #1

    Enrichment analysis with DAVID tool - question

    Hi All,

    I am still new in the field and I have a question please.

    I have a dataset of gene expressions and I am running biclustering methods over them. The dataset is colon cancer dataset, When I get the new biclusters I want to do biological validation; enrichment analysis to find how many genes are enriched in each bicluster. I want to use DAVID tool for that.
    My question is when I upload my gene set to DAVID tool, I choose "Functional Annotation Clustering" then I have set of clusters for the set of genes that I uploaded with different gene enrichment score. How can I find "Proportion of biclusters significantly enriched" as it has been done in Figure 3 of this paper "A systematic comparison and evaluation of biclustering methods
    for gene expression data"
    http://bioinformatics.oxfordjournals.org/content/22/9/1122.full.pdf+html


    Any help please? Any hint really appreciated.

    Could anyone with experience direct me please.
    Thanks!
    Last edited by ComputGuy; 09-23-2013, 11:23 AM.
    Tags: david tool, enrichment, gene expression
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