Seqanswers Leaderboard Ad

Collapse

Announcement

Collapse
No announcement yet.
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • Determine ethnicity from exome sequence

    I have data from 40 exomes and they are from de-identified post-mortem samples.

    There are many SNPs that have a higher frequency in Asian populations compared to Europeans, for example. When I compare my data to available SNP frequencies I would like to match the ethnicity. Have the collective observed alleles at such sites been used to determine the ethnicity from exome data?

    Also, I have been able to reconstruct the Mitochondrial DNA sequence from off-target reads, using MitoSeek. I can determine the mitochondrial haplotype using Mitotool website, and since particular mitochondrial haplogroups can be enriched in ethnic groups, can this extra information support ethnicity?

    Any thoughts or comments welcome.

  • #2

    Comment

    Latest Articles

    Collapse

    • seqadmin
      Choosing Between NGS and qPCR
      by seqadmin



      Next-generation sequencing (NGS) and quantitative polymerase chain reaction (qPCR) are essential techniques for investigating the genome, transcriptome, and epigenome. In many cases, choosing the appropriate technique is straightforward, but in others, it can be more challenging to determine the most effective option. A simple distinction is that smaller, more focused projects are typically better suited for qPCR, while larger, more complex datasets benefit from NGS. However,...
      10-18-2024, 07:11 AM
    • seqadmin
      Non-Coding RNA Research and Technologies
      by seqadmin




      Non-coding RNAs (ncRNAs) do not code for proteins but play important roles in numerous cellular processes including gene silencing, developmental pathways, and more. There are numerous types including microRNA (miRNA), long ncRNA (lncRNA), circular RNA (circRNA), and more. In this article, we discuss innovative ncRNA research and explore recent technological advancements that improve the study of ncRNAs.

      Nobel Prize for MicroRNA Discovery
      This week,...
      10-07-2024, 08:07 AM

    ad_right_rmr

    Collapse

    News

    Collapse

    Topics Statistics Last Post
    Started by seqadmin, Yesterday, 06:09 AM
    0 responses
    10 views
    0 likes
    Last Post seqadmin  
    Started by seqadmin, 10-30-2024, 05:31 AM
    0 responses
    13 views
    0 likes
    Last Post seqadmin  
    Started by seqadmin, 10-24-2024, 06:58 AM
    0 responses
    22 views
    0 likes
    Last Post seqadmin  
    Started by seqadmin, 10-23-2024, 08:43 AM
    0 responses
    52 views
    0 likes
    Last Post seqadmin  
    Working...
    X