I am looking for a sample algorithm or a script for Mendelian inheritance filtering. I have a table of variants and each row represents a unique variation that is shared or not between different members of a large family. I imagine that there should be a meta file I supply with the Mendelian structure information and my script should read that and filter my data based on that meta data. The result should be these variants fit an autosomal recessive inheritance patterns etc. I can provide the expected inheritance pattern in the meta data file as well but the ideal script should be able figure that out as well. Does anyone know anything similar to this before I start melting my brain on this hopefully not reinventing the wheel? Python preferred but a general algorithm is more than OK.
Thanks
Thanks
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