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  • Jeannine
    replied
    Any update on that?
    I've got a list of potential ncRNAs, but have no idea what to do next. It looks like most people do over-expression/knockdown experiments to identify ncRNA targets, but that's not feasible for a list of 100-200 ncRNAs...

    Any help or suggestions would be highly appreciated!

    Thanks,
    Jeannine

    Leave a comment:


  • TiborNagy
    replied
    I have found only this:
    Recent studies demonstrating the existence of special noncoding "antisense" RNAs used in post transcriptional gene regulation have received considerable attention. These RNAs are synthesized naturally to control gene expression in C. elegans, Drosophila, and other organisms; they are known to regula …

    Leave a comment:


  • id0
    started a topic lncRNA target prediction

    lncRNA target prediction

    There are many tools for predicting miRNA targets. Does something like that exist for lncRNAs?

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  • seqadmin
    Essential Discoveries and Tools in Epitranscriptomics
    by seqadmin




    The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...
    04-22-2024, 07:01 AM
  • seqadmin
    Current Approaches to Protein Sequencing
    by seqadmin


    Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
    04-04-2024, 04:25 PM

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