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  • cr234
    Junior Member
    • Dec 2013
    • 2

    #1

    Issue with tabix - Could not load .tbi index

    I've been trying to generate vcf.gz files and associated .vcf.gz.tbi indexes for multiple .vcf files simultaneously. I first ran into the problem of bgzip only creating one .vcf.gz file when I ran;

    bgzip *.vcf

    However I got round this by running the command several (400) times;

    n=0; while [[ $n -lt 400 ]]; do bgzip -i *.vcf; n=$((n+1)); done

    I wanted to do the same for tabix so tried to use;

    n=0; while [[ $n -lt 400 ]]; do tabix -p vcf *.vcf.gz; n=$((n+1)); done

    However this gives me the error;

    'Could not load .tbi index of file1.vcf.gz'

    This is the first file in the list. Tabix works just fine if I use;

    tabix -p vcf file1.vcf.gz

    However I don't want to have to type out ~400 odd .vcf.gz file names. Does anyone know why I am having this issue?

    Thanks.
  • GenoMax
    Senior Member
    • Feb 2008
    • 7142

    #2
    How about:

    Code:
    for f in *.vcf.gz
    do[INDENT]tabix -p vcf $f[/INDENT]
    done
    as a one liner
    Code:
    for f in *.vcf.gz; do tabix -p vcf $f; done
    Last edited by GenoMax; 08-26-2014, 08:34 AM.

    Comment

    • cr234
      Junior Member
      • Dec 2013
      • 2

      #3
      Yep that works great, thanks a lot!

      Comment

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