Comparative genomics

[Jean_Guillaume777]

Hi everyone,
I begin a new study in comparative genomics between two strains from same species (a reference strain and a new one freshly assembled and annotated). I need to find all the differences between the two chromosomal sequences, except SNPs. Up to now, I have used ACT to visualize the genomic alignment and I have listed all the differences manually. I can say for now that the majority of differences are caused by movement of insertion sequences (ISs).

Now that I know the nature of the all differences between the two genomes, I want to use a web server to do the sames analyses that me, just to check the accuracy of my results

[Antony03]

Just a little up. I have the same question.

[milo0615]

Hi everyone,
I begin a new study in comparative genomics between two strains from same species (a reference strain and a new one freshly assembled and annotated). I need to find all the differences between the two chromosomal sequences, except SNPs. Up to now, I have used ACT to visualize the genomic alignment and I have listed all the differences manually. I can say for now that the majority of differences are caused by movement of insertion sequences (ISs).

Now that I know the nature of the all differences between the two genomes, I want to use a web server to do the sames analyses that me, just to check the accuracy of my results

Hi Jean,

were you able to figure it out? Please share.

[AntonioRFranco]

Take a look to this page VISTA Tool. I sucessfully have recently compared two full steptococcus genomes. I eventually process the information that this service gave me to figure out the genes present in one strain that were missing in the other

[Jean_Guillaume777]

Thank you AntonioRFranco!

I will try VISTA Tool for my genomic comparison.